Geometric-phase microscopy (GPM) uses changes in the phase of light passing through biological specimens to yield high-resolution and high-contrast images, instead of relying on the attenuation of light used conventionally. Polarization optics and a spatial light modulator generate spatially variant polarization states of light that interact with the sample, creating a relative phase shift between transmitted and reflected light waves. By analyzing the phase information, GPM can reveal details not visible with other microscopy techniques. GPM is an effective non-invasive tool for live cell and tissue studies, with potential to enhance biological systems knowledge.
Category: Liquid Crystal Polarization Grating Resources
Liquid Crystal Polarization Grating Resources
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Geometric-Phase Microscopy for Quantitative Phase Imaging of Isotropic, Birefringent and Space-Variant Polarization Samples
Geometric-phase microscopy (GPM) uses changes in the phase of light passing through biological specimens to yield high-resolution and high-contrast images, instead of relying on the attenuation of light used conventionally. Polarization optics and a spatial light modulator generate spatially variant polarization states of light that interact with the sample, creating a relative phase shift between transmitted and reflected light waves. By analyzing the phase information, GPM can reveal details not visible with other microscopy techniques. GPM is an effective non-invasive tool for live cell and tissue studies, with potential to enhance biological systems knowledge.